Citation

Tedeschi G, Bittencourt PR, Smith AT, Richens A. Psychopharmacology 1983; 79(2-3): 190-192.

Copyright

(Copyright © 1983, Holtzbrinck Springer Nature Publishing Group)

DOI

unavailable

PMID

6405428

Abstract

Healthy volunteers received single oral or intravenous doses of d-amphetamine sulphate (15 mg) and placebo in a double blind randomized design. Peak velocity of horizontal saccadic eye movements, saccade duration, saccade reaction time and smooth pursuit velocity were measured at intervals up to 1 h (IV) and 6 h (oral) after drug administration. Amphetamine produced no significant effect on saccadic and smooth-pursuit eye movements after oral administration. However, intravenous amphetamine abolished the effect of fatigue on saccadic movements and significantly (P less than 0.01) shortened saccadic reaction time.

Language: en