Citation

Kaplan C, Kocaman SA, Durakoğlugil ME, Kaya E, Senol MG. Herz 2013; 38(6): 683-684.

Vernacular Title

Schmerzbedingte kardiale Synkope : Bericht über einen auf Duloxetintherapie ansprechenden Fall.

Affiliation

Department of Neurology, Bursa Military Hospital, Bursa, Turkey.

Copyright

(Copyright © 2013, Holtzbrinck Springer Nature Publishing Group)

DOI

10.1007/s00059-012-3734-6

PMID

23588599

Abstract

Neurocardiogenic syncope comprises situations triggered by neurological reflexes resulting in abnormal responses of the neurocardiovascular system that cause loss of consciousness. A vast number of clinical conditions may cause this disorder including pain, defecation, micturition, swallowing, cough, sudden fear or excitement, exercise, and long-time standing. Treatment options for syncope prevention are not satisfactory. Several agents were used for pharmacological treatment without success. Selective inhibitors of neuronal norepinephrine transporter (NET) like duloxetine may play a role in neurally mediated syncope by increasing synaptic norepinephrine levels. Therefore, we report the effect of duloxetine in a patient with pain-induced syncope resistant to standard regimens.

Language: en