Citation

Warren RJ. J. Can. Soc. Forensic Sci. 1998; 31(4): 313-317.

Copyright

(Copyright © 1998, Canadian Society of Forensic Science, Publisher Informa - Taylor and Francis Group)

DOI

10.1080/00085030.1998.10757126

PMID

unavailable

Abstract

A case report of a fatality involving the suicidal injection of rocuronium, a neuromuscular blocker, is presented. A gas chromatographic (nitrogen/phosphorus detection) method for the quantitative determination of rocuronium in postmortem blood is described. This procedure involves an iodide ion-pair extraction followed by derivatization with MTBSTFA. The rocuronium postmortem blood concentration was found to be 0.74 μg/mL. The mass spectrum of the t-BDMS derivative of rocuronium is also provided. © 1998 Taylor and Francis Group, LLC.

Language: en

Keywords

adult; article; autopsy; case report; drug blood level; gas chromatography; human; iodide; ion pair extraction; male; mass spectrometry; nitrogen; phosphorus; quantitative assay; rocuronium; suicide