Citation

Avanzi M, Baratti M, Cabrini S, Uber E, Brighetti G, Bonfà F. Parkinsonism Relat. Disord. 2008; 14(3): 257-258.

Affiliation

Division on Addiction, Hospital of Cortemaggiore, AUSL of Piacenza, Italy. maurizioava@hotmail.com

Copyright

(Copyright © 2008, Elsevier Publishing)

DOI

10.1016/j.parkreldis.2007.04.006

PMID

17561433

Abstract

We report two male patients with Parkinson's disease who developed compulsive risk-seeking driving behaviour as a result of self-administering high doses of L-dopa despite an adequate therapeutic response at lower doses. When L-dopa reduction was feasible, it resulted in cessation of unsafe driving. We believe that this impairment in driving performance, due to deliberate overuse of dopaminergic medication, should be included as a new behavioural phenomenon in dopamine dysregulation syndrome.

Language: en