Citation

Slattery A, Liebelt E, Gaines LA. Curr. Opin. Ophthalmol. 2014; 25(6): 519-523.

Affiliation

aRegional Poison Control Center, Children's of Alabama bDepartment of Pediatrics, University of Alabama Birmingham School of Medicine, Birmingham, Alabama, USA.

Copyright

(Copyright © 2014, Lippincott Williams and Wilkins)

DOI

10.1097/ICU.0000000000000103

PMID

25226509

Abstract

PURPOSE OF REVIEW: Ocular effects resulting from medications assist toxicologists in determining substances involved when treating a poisoned patient. The intention of this review is to discuss the most common ocular effects, the medications that cause them, and the mechanisms by which they occur. RECENT FINDINGS: According to National Poison Data System, the most common reported ocular effects following a drug ingestion/injection/inhalation are mydriasis, miosis, and nystagmus. The most common drug/drug classes reported to a regional poison control center causing these ocular effects include the following: first, mydriasis - amphetamines and diphenhydramine; second, miosis - clonidine and opioids; third, nystagmus - dextromethorphan. However, many other drugs/substances can cause these effects along with other systemic effects. SUMMARY: Ocular findings are a pertinent component of any patient assessment involving therapeutic and/or toxic exposure to medications and other substances.

Language: en