Citation

Pan LA, Ramos L, Segreti A, Brent DA, Phillips ML. Br. J. Psychiatry 2014; 206(4): 339-340.

Affiliation

Lisa A. Pan, MD, Lisa Ramos, BS, AnnaMaria Segreti, BS, David A. Brent, MD, Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, USA; Mary L. Phillips, MD(Cantab), Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, USA, and Department of Psychological Medicine, School of Medicine, Cardiff University, Cardiff, UK.

Copyright

(Copyright © 2014, Royal College of Psychiatry)

DOI

10.1192/bjp.bp.114.151316

PMID

25497300

Abstract

The extent to which observed differences in emotion processing and regulation neural circuitry in adolescents with a history of suicide attempt are paralleled by structural differences is unknown. We measured brain cortical thickness and grey- and white-matter volumes in 100 adolescents: 28 with a history of suicide attempt and major depressive disorder (MDD); 31 with a history of MDD but no suicide attempt; and a healthy control group (n = 41). The first group compared with controls showed reduction in grey-matter volume in the right superior temporal gyrus (BA38), a region important for social emotion processing.

Language: en