Citation

Montes J, Cheng B, Diamond B, Doorish C, Mitsumoto H, Gordon PH. Amyotroph. Lateral Scler. 2007; 8(5): 292-295.

Affiliation

Department of Neurology, College of Physicians and Surgeons, The Eleanor and Lou Gehrig MDA/ALS Research Center.

Copyright

(Copyright © 2007, Informa - Taylor and Francis Group)

DOI

10.1080/17482960701435931

PMID

17852012

Abstract

There are few functionally meaningful clinical measures used to guide management of patients with ALS. Falls are common, can be debilitating, and result in increased health care costs. We assessed the performance and ability to predict falls of the Timed Up and Go (TUG) test, which quantifies walking ability, in a prospective longitudinal study. Thirty-one patients underwent six monthly TUG, ALSFRS-R, forced vital capacity, muscle testing (MMT) and quality of life assessments. Linear and generalized linear mixed effects models assessed the associations among variables and ability to predict falls. The increase in TUG time was linear over six months, and TUG time was negatively associated with ALSFRS-R (p

Language: en